S. 4321 would amend statutes that direct the organization and operation of the Marine Debris Foundation, a nongovernmental entity. The bill also would direct the foundation to develop best practices for conducting outreach to Indian tribes and tribal governments. CBO estimates that enacting S. 4321 would not affect direct spending, revenues, or spending subject to appropriation. The bill contains no intergovernmental or private-sector mandates as defined in the Unfunded Mandates Reform Act.